Problems in the Organic Chemistry of Natural Products
DTU Department of Chemistry
To be trained in the organic chemistry that forms the basis for synthesis and analysis of natural products.
Learning objectives:
A student who has met the objectives of the course will be able to:
- Present research project design and results orally, in a clear, concise manner
- Be able to discuss one's own chemistry research at an international high level
- Be able to discuss ongoing research at DTU Chemistry at an intermediary level
- Solve complex problems within natural product synthesis
- Assign the structure of a natural product from spectroscopic data
- Suggest a realistic retrosynthetic analysis of complex secondary metabolites
- Apply catalytic, reagent and substrate based stereocontrol in synthesis
- Work individually and in teams with synthetic problems
- Present solutions at meetings and partake in a discussion of the details
- Apply the chemical literature as a basis for new solutions to synthetic problems
- Integrate knowledge of reaction mechanisms in synthetic planning
- Be proficient at acquiring and processing 1D and 2D NMR data
Contents:
The students should devise solutions to various problems in organic chemistry working either alone or in groups. The problems will include the following: - retrosynthetic analysis of new organic molecules and natural products - structural determination of natural products - stereoselective synthesis of complex molecules There will also be mandatory NMR training sessions.