Introduction to omics for clinical researchers Part 1
Graduate School of Health and Medical Sciences at University of Copenhagen
This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD Students from NorDoc member faculties. All other participants must pay the course fee.
Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from NorDoc member faculties. After the enrollment deadline, available seats will be allocated to applicants on the waiting list.
Learning objectives
A student who has met the objectives of the course will be able to:
1. Knowledge (part 1): understand and discuss the fundamental principles underlying OMICS analyses including genomics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, microbiota/metagenomics as well as bioinfomatics.
2. Knowledge (part 2): understand and discuss key aspects of the methods, techniques and interpretation of applied OMICs analyses including:
i) the impact of genome variation on health and disease,
ii) the potential applications of modern techniques to study genomic variation and epigenetics,
iii) the strengths and limitations of translation of genome variation, epigenetics and genetic epidemiology,
iv) the application of RNA sequencing,
v) the principles and application of transcriptomic profiling of tissue, single cells, and singele cell nuclei,
vi) the application, characteristics and principles of tissue and plasma proteomics,
vii) the use of mass spectrometry for proteomic analyses and protein databases,
viii) the characteristics and principles of lipidomics, metabolomics, and the interaction between microbiota and metagenomics
ix) the basic aspects of bioinformatics including machine learning, integration of omic data and visualization.
3. Skills (part 1): Understand and discuss the fundamental aspects of studies using genomics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, and metagenomics as well as bioinformatics in humans.
4. Skills (part 2): i) Critically evaluate results from studies using the techonologies covered in the course, ii) Design an appropriate study evaluating OMICS in human diseases.
5. Competences (part 1): Understand and explain central aspects of key aspects of OMICS studies.
6. Competences: Understand and explain central aspects of applied OMICS studies (part 2).
Content
The main themes covered in the course are genomics, epigenomics, transcriptomics, proteomics, metabolomic, lipidomics, metagenomics, and bioinformatics. Part 1 covers the fundamental aspects and part 2 includes more detailed knowledge including applied OMICS studies.
Participants
Participants must be enrolled as PhD students at the Copenhagen University, Faculty of Health and Medical Sciences, University of Copenhagen.
Relevance to graduate programmes
The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH:
All graduate programmes
Language
English
Form
The course is organized as an 17-hour online course (part 1) in Absalon followed by a 2,5-day course with lectures (part 2). Both courses include exercises. We recommend that part 1 is completed before enrolment in part 2, but the two courses may be taken independently.
Part 1 is recorded and an online on-demand course consisting of modules that may be taken by the students when it is convenient for them within a two week period. This is done to increase the flexibility and will also make it possible for a larger number of students to enrol. At the end of each online module, participants have to compete multiple choice questionnaires and a written assigmnent to ensure that the course is interactive.
Course director
- Lise Lotte Gluud, Professor, Copenhagen University Hospital Hvidovre, University of Copenhagen, lise.lotte.gluud.01@regionh.dk
- Nicolai J. Wewer Albrechtsen , Associate Professor, Novo Nordisk Foundation, Center for Protein Research, University of Copenhagen, nicolai.albrechtsen@sund.ku.dk
Teachers
- Stefan Stender, Stefan.Stender@regionh.dk, Senior Registrar, Department of Clinical Biochemistry, Rigshospitalet,
- Peter Davidsen, peter.davidsen@ferring.com, Computational Biologist, Ferring
- Lili Niu, lili.niu@cpr.ku.dk, PhD student, Novo Nordisk Foundation Center for Protein Research, Clinical Proteomics, University of Copenhagen,
- Karolina Sulek, karolina.sulek@cpr.ku.dk, Associate Professor, Mann Group, University of Copenhagen,
- Tune H Pers, tune.pers@sund.ku.dk, Associate Professor, Novo Nordisk Foundation, Center for Basic Metabolic Research, University of Copenhagen,
- Majken K Jensen, maje@sund.ku.dk, Professor, Section of Epidemiology, University of Copenhagen,
- Karina Banasik, karina.banasik@cpr.ku.dk, Associate Professor, Novo Nordisk Foundation Center for Protein Research, Brunak Group,
- Andreas Mund, andreas.mund@cpr.ku.dk, Associate Professor, Novo Nordisk Foundation Center for Protein Research,Proteomics Program,
- Ana Rita Freitas Colaco, rita.colaco@cpr.ku.dk, PostDoc, Novo Nordisk Foundation Center for Protein Research,Proteomics Program,
- Annelaura Bach Nielsen, annelaura.bach@cpr.ku.dk, PostDoc, Novo Nordisk Foundation Center for Protein Research,Proteomics Program
Konstantinos Dimopoulos, konstantinos.dimopoulos@regionh.dk, Department of Biochemistry, Bispebjerg
Holleboom, A.G., a.g.holleboom@amsterdamumc.nl, Research Institute, Amsterdam Gastroenterology, Endocrinology and Metabolism
Dates
Part 1, the online course, will be available 7 - 21 October 2024 and 10 - 24 March 2025.
Part 2 will take place 12 - 14 May 2025.
Course location
Part 1: online.
Part 2: Mærsk Tower, University of Copenhagen.
Registration
Please register before
Part 1: 18 September 2024 for the October course and 12 February 2025 for the course in March 2025.
Part 2: 11 March 2025 for the course in May
Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment.
Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.